abstract：OBJECTIVES:To develop a theory-led framework to inform reviewers' understanding of what, how, and why health care interventions may lead to differential effects across socioeconomic groups. STUDY DESIGN AND SETTING:A metaframework approach combined two theoretical perspectives (socioeconomic health inequalities and co...

journal_title：Journal of clinical epidemiology

authors： Maden M,McMahon N,Booth A,Dickson R,Paisley S,Gabbay M

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:Constructs capturing health or functioning can have reflective and/or formative measurement models. Although a construct's measurement model has extensive implications on the construction, validation, and use of a measurement instrument, measurement models are frequently wrongly or not explicitly specified. ...

journal_title：Journal of clinical epidemiology

authors： Fleuren BPI,van Amelsvoort LGPM,Zijlstra FRH,de Grip A,Kant I

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The Kaplan-Meier method may overestimate absolute mortality risk (AMR) in the presence of competing risks. Urgent heart transplantation (UHT) and ventricular assist device implantation (VADi) are important competing events in heart failure. We sought to quantify the extent of bias of the Kaplan-Meier method i...

journal_title：Journal of clinical epidemiology

authors： Scrutinio D,Guida P,Passantino A,Ammirati E,Oliva F,Lagioia R,Frigerio M

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To determine the status of dementia care services and workforce in selected public and private hospitals and geriatric care facilities in the Philippines. STUDY DESIGN AND SETTING:Framework analysis of 54 key informant interviews, 4 focus group discussions, and survey of 167 workers in 26 purposively selecte...

journal_title：Journal of clinical epidemiology

authors： Dela Vega SF,Cordero CP,Palapar LA,Garcia AP,Agapito JD

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:To study the statistical power of randomized clinical trials and examine developments over time. STUDY DESIGN AND SETTING:We analyzed the statistical power in 136,212 clinical trials between 1975 and 2014 extracted from meta-analyses from the Cochrane database of systematic reviews. We determined study powe...

journal_title：Journal of clinical epidemiology

authors： Lamberink HJ,Otte WM,Sinke MRT,Lakens D,Glasziou PP,Tijdink JK,Vinkers CH

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Cochrane acute respiratory infections (ARIs) group conducts systematic reviews of the evidence for treatment and prevention of ARIs. We report the results of a prioritization project, aiming to identify highest priority systematic review topics. STUDY DESIGN/SETTING:The project consisted of two phases. Phase...

journal_title：Journal of clinical epidemiology

authors： Scott AM,Clark J,Dooley L,Jones A,Jones M,Del Mar C

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To assess the effects of abbreviated literature searches on evidence syntheses conclusions. STUDY DESIGN AND SETTING:We randomly selected 60 Cochrane reviews of clinical interventions and repeated literature searches using 14 abbreviated approaches (combinations of MEDLINE, Embase, CENTRAL with and without s...

journal_title：Journal of clinical epidemiology

authors： Nussbaumer-Streit B,Klerings I,Wagner G,Heise TL,Dobrescu AI,Armijo-Olivo S,Stratil JM,Persad E,Lhachimi SK,Van Noord MG,Mittermayr T,Zeeb H,Hemkens L,Gartlehner G

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:To develop the first item bank to measure stress resilience (SR) in clinical populations. STUDY DESIGN AND SETTING:Qualitative item development resulted in an initial pool of 131 items covering a broad theoretical SR concept. These items were tested in n = 521 patients at a psychosomatic outpatient clinic. ...

journal_title：Journal of clinical epidemiology

authors： Obbarius N,Fischer F,Obbarius A,Nolte S,Liegl G,Rose M

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:To explore how the concept of randomization is described by clinicians and understood by patients in randomized controlled trials (RCTs) and how it contributes to patient understanding and recruitment. STUDY DESIGN AND SETTING:Qualitative analysis of 73 audio recordings of recruitment consultations from fiv...

journal_title：Journal of clinical epidemiology

authors： Jepson M,Elliott D,Conefrey C,Wade J,Rooshenas L,Wilson C,Beard D,Blazeby JM,Birtle A,Halliday A,Stein R,Donovan JL,CSAW study group.,Chemorad study group.,POUT study group.,ACST-2 study group.,OPTIMA prelim study group.

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To assess the cross-cultural adaptations of the Roland-Morris Disability Questionnaire (RMDQ). STUDY DESIGN AND SETTING:English and Chinese databases were searched through December 2017. Cross-cultural adaptation and measurement properties were evaluated using the Guidelines for the Process of Cross-Cultural...

journal_title：Journal of clinical epidemiology

authors： Yao M,Zhu S,Tian ZR,Song YJ,Yang L,Wang YJ,Cui XJ

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:To evaluate how the rank probabilities obtained from network meta-analysis (NMA) change with the use of increasingly stringent criteria for the relative effect comparing two treatments which ranks one treatment better than the other. STUDY DESIGN AND SETTING:Systematic survey and reanalysis of published dat...

journal_title：Journal of clinical epidemiology

authors： Brignardello-Petersen R,Johnston BC,Jadad AR,Tomlinson G

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Regression discontinuity (RD) is a quasi-experimental design that may provide valid estimates of treatment effects in case of continuous outcomes. We aimed to evaluate validity and precision in the RD design for dichotomous outcomes. STUDY DESIGN AND SETTING:We performed validation studies in three large ran...

journal_title：Journal of clinical epidemiology

authors： van Leeuwen N,Lingsma HF,Mooijaart SP,Nieboer D,Trompet S,Steyerberg EW

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate how often the European Medicines Agency (EMA) has authorized drugs based on nonrandomized studies and whether there is an association between treatment effects and EMA preference for further testing in randomized clinical trials (RCTs). STUDY DESIGN AND SETTING:We revie...

journal_title：Journal of clinical epidemiology

authors： Djulbegovic B,Glasziou P,Klocksieben FA,Reljic T,VanDenBergh M,Mhaskar R,Ioannidis JPA,Chalmers I

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To demonstrate analytic approaches for matched studies where two controls are linked to each case and events are accumulating counts rather than binary outcomes. A secondary intent is to clarify the distinction between total risk and excess risk (unmatched vs. matched perspectives). STUDY DESIGN AND SETTING...

journal_title：Journal of clinical epidemiology

authors： Redelmeier DA,Tibshirani RJ

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To outline contemporary and novel developments for the presentation and reporting of syntheses of qualitative, implementation, and process evaluation evidence and provide recommendations for the use of reporting guidelines. STUDY DESIGN AND SETTING:An overview of reporting guidelines for qualitative, implem...

journal_title：Journal of clinical epidemiology

authors： Flemming K,Booth A,Hannes K,Cargo M,Noyes J

更新日期：2018-05-01 00:00:00

abstract：:The Cochrane Qualitative and Implementation Methods Group develops and publishes guidance on the synthesis of qualitative and mixed-method implementation evidence. Choice of appropriate methodologies, methods, and tools is essential when developing a rigorous protocol and conducting the synthesis. Cochrane authors who...

journal_title：Journal of clinical epidemiology

authors： Noyes J,Booth A,Flemming K,Garside R,Harden A,Lewin S,Pantoja T,Hannes K,Cargo M,Thomas J

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the use of three treatment-effect measures in the analysis of randomized trials using a time-to-event endpoint and assess their influence on the results. STUDY DESIGN AND SETTING:A recent equivalence trial showed discordant results with the use of different measures....

journal_title：Journal of clinical epidemiology

authors： Abulizi X,Flandre P

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate how frequently complex interventions are shown to be superior to routine care in general practice-based cluster-randomized controlled studies (c-RCTs) and to explore whether potential differences explain results that come out in favor of a complex intervention. STUDY DE...

journal_title：Journal of clinical epidemiology

authors： Siebenhofer A,Paulitsch MA,Pregartner G,Berghold A,Jeitler K,Muth C,Engler J

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:Emergency department triage systems can be considered prediction rules with an ordinal outcome, where different directions of misclassification have different clinical consequences. We evaluated strategies to compare the performance of triage systems and aimed to propose a set of performance measures that sh...

journal_title：Journal of clinical epidemiology

authors： Zachariasse JM,Nieboer D,Oostenbrink R,Moll HA,Steyerberg EW

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:Researchers need to be confident about the reliability of epidemiologic studies that quantify medication use through self-report. Some evidence suggests that psychiatric medications are systemically under-reported. Modern record linkage enables validation of self-report with national prescribing data as gold...

journal_title：Journal of clinical epidemiology

authors： Hafferty JD,Campbell AI,Navrady LB,Adams MJ,MacIntyre D,Lawrie SM,Nicodemus K,Porteous DJ,McIntosh AM

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to determine the applicability of utilizing the N-of-1 method for deprescribing trials in older adults. STUDY DESIGN AND SETTING:Systematic review of any human studies conducted in older adults (≥50 years), deprescribing any long-term treatment over less than a year using the...

journal_title：Journal of clinical epidemiology

authors： Clough AJ,Hilmer SN,Naismith SL,Kardell LD,Gnjidic D

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The impact of disease on population health is most commonly estimated by the population attributable fraction (PAF), or less commonly by the excess risk, an alternative measure that estimates the absolute risk of disease in the population that can be ascribed to the exposure. Using chronic airflow obstructio...

journal_title：Journal of clinical epidemiology

authors： Burney P,Minelli C

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:Interpretation of clinical research findings using the paradigm of null hypothesis significance testing has a number of limitations. These include arbitrary dichotomization of results, lack of incorporation of study power and prior probability, and the confusing use of conditional probability. This study aim...

journal_title：Journal of clinical epidemiology

authors： Adams NG,O'Reilly G

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to identify and describe critical appraisal tools designed for assessing the quality of evidence (QoE) and/or strength of recommendations (SoRs) related to health care-related tests and diagnostic strategies (HCTDSs). STUDY DESIGN AND SETTING:We conducted a systematic review ...

journal_title：Journal of clinical epidemiology

authors： Mustafa RA,Wiercioch W,Falavigna M,Zhang Y,Ivanova L,Arevalo-Rodriguez I,Cheung A,Prediger B,Ventresca M,Brozek J,Santesso N,Bossuyt P,Garg AX,Lloyd N,Lelgemann M,Bühler D,Schünemann HJ

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:The objective of the study was to describe and compare current practices in developing guidelines about the use of healthcare-related tests and diagnostic strategies (HCTDS). STUDY DESIGN AND SETTING:We sampled 37 public health and clinical practice guidelines about HCTDS from various sources without langua...

journal_title：Journal of clinical epidemiology

authors： Mustafa RA,Wiercioch W,Arevalo-Rodriguez I,Cheung A,Prediger B,Ivanova L,Ventresca M,Brozek J,Santesso N,Bossuyt P,Garg AX,Lloyd N,Lelgemann M,Bühler D,Schünemann HJ

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:The decision to make protocols of phase III randomized controlled trials (RCTs) publicly accessible by leading journals was a landmark event in clinical trial reporting. Here, we compared primary outcomes defined in protocols with those in publications describing the trials and in trial registration. STUDY ...

journal_title：Journal of clinical epidemiology

authors： Zhang S,Liang F,Li W

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to determine whether disagreements among multiple data sources affect systematic reviews of randomized clinical trials (RCTs). STUDY DESIGN AND SETTING:Eligible RCTs examined gabapentin for neuropathic pain and quetiapine for bipolar depression, reported in public (e.g., jour...

journal_title：Journal of clinical epidemiology

authors： Mayo-Wilson E,Li T,Fusco N,Bertizzolo L,Canner JK,Cowley T,Doshi P,Ehmsen J,Gresham G,Guo N,Haythornthwaite JA,Heyward J,Hong H,Pham D,Payne JL,Rosman L,Stuart EA,Suarez-Cuervo C,Tolbert E,Twose C,Vedula S,Dicke

更新日期：2017-11-01 00:00:00

abstract：:Results from pragmatic trials should reflect the comparative treatment effects encountered in patients in real-life clinical practice to guide treatment decisions. Therefore, pragmatic trials should focus on outcomes that are relevant to patients, clinical practice, and treatment choices. This sixth article in the ser...

journal_title：Journal of clinical epidemiology

authors： Welsing PM,Oude Rengerink K,Collier S,Eckert L,van Smeden M,Ciaglia A,Nachbaur G,Trelle S,Taylor AJ,Egger M,Goetz I,Work Package 3 of the GetReal Consortium.

更新日期：2017-10-01 00:00:00

abstract：:Pragmatic trials aim to inform clinical decision making by measuring the effect of a treatment in clinical practice. The purpose of the PRECIS-2 tool is to support in designing a truly pragmatic trial. We comment on a study by Forbes et al., who assessed the applicability of the PRECIS-2 tool. The tool will prove part...

journal_title：Journal of clinical epidemiology

authors： Groenwold RHH,Dekkers OM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Once a proposed topic has been identified for a systematic review and has undergone a question formulation stage, a protocol must be developed that specifies the scope and research questions in detail and outlines the methodology for conducting the systematic review. RATIONALE:Framework modifications are of...

journal_title：Journal of clinical epidemiology

authors： Butler M,Epstein RA,Totten A,Whitlock EP,Ansari MT,Damschroder LJ,Balk E,Bass EB,Berkman ND,Hempel S,Iyer S,Schoelles K,Guise JM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:A comprehensive picture of population health status can be captured by the incorporation of patient-reported outcome measures into population health monitoring. OBJECTIVE:The aim of the study was to identify the current state, opportunities, and future research related to the utilization of patient-reported...

journal_title：Journal of clinical epidemiology

authors： Mamiya H,Lix LM,Gardner W,Bartlett SJ,Ahmed S,Buckeridge DL

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:The objectives of this study were to evaluate the current state of reporting and handling of effect modification in network meta-analyses (NMAs) and perform exploratory analyses to identify variables that are potentially associated with incomplete reporting of effect modifiers in NMAs. STUDY DESIGN AND SETTI...

journal_title：Journal of clinical epidemiology

authors： Kovic B,Zoratti MJ,Michalopoulos S,Silvestre C,Thorlund K,Thabane L

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To illustrate and discuss current and proposed new concepts of effect size (ES) quantification and significance, with a focus on statistical and clinical/subjective interpretation and supported by empirical examples. STUDY DESIGN AND SETTINGS:Different methods for determining minimal clinically important dif...

journal_title：Journal of clinical epidemiology

authors： Angst F,Aeschlimann A,Angst J

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:The objective was to estimate the presence and extent to which potentially unnecessary and therefore maybe wasteful clinical trials regarding relevant interventions and outcomes in major clinical areas had been conducted. STUDY DESIGN AND SETTING:From current Cochrane collaboration systematic reviews in majo...

journal_title：Journal of clinical epidemiology

authors： Storz-Pfennig P

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:Complex longitudinal sampling and the observational structure of patient registers in health services research are associated with methodological challenges regarding data management and statistical evaluation. We exemplify common pitfalls and want to stimulate discussions on the design, development, and dep...

journal_title：Journal of clinical epidemiology

authors： Bluhmki T,Bramlage P,Volk M,Kaltheuner M,Danne T,Rathmann W,Beyersmann J

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:Explicit reporting of absolute measures is important to ensure treatment effects are correctly interpreted. We examined the extent to which authors report absolute effects for patient-important outcomes in abstracts of systematic review (SR). STUDY DESIGN AND SETTING:We searched OVID MEDLINE and Cochrane Da...

journal_title：Journal of clinical epidemiology

authors： Agarwal A,Johnston BC,Vernooij RW,Carrasco-Labra A,Brignardello-Petersen R,Neumann I,Akl EA,Sun X,Briel M,Busse JW,Ebrahim S,Granados CE,Iorio A,Irfan A,Martínez García L,Mustafa RA,Ramirez-Morera A,Selva A,Solà I,S

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Conduct a systematic review of pediatric randomized controlled trials (RCTs) published in high-impact journals to assess the reporting of primary outcomes and the psychometric properties of their measures. STUDY DESIGN AND SETTING:Systematic review with screening and simultaneous data extraction conducted by...

journal_title：Journal of clinical epidemiology

authors： Bhaloo Z,Adams D,Liu Y,Hansraj N,Hartling L,Terwee CB,Vohra S

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Intervention Modeling Experiments (IMEs) are a way of developing and testing behavior change interventions before a trial. We aimed to test this methodology in a Web-based IME that replicated the trial component of an earlier, paper-based IME. STUDY DESIGN AND SETTING:Three-arm, Web-based randomized evaluat...

journal_title：Journal of clinical epidemiology

authors： Treweek S,Francis JJ,Bonetti D,Barnett K,Eccles MP,Hudson J,Jones C,Pitts NB,Ricketts IW,Sullivan F,Weal M,MacLennan G

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To systematically review methodological articles which focus on nonpublication of studies and to describe methods of detecting and/or quantifying and/or adjusting for dissemination in meta-analyses. To evaluate whether the methods have been applied to an empirical data set for which one can be reasonably conf...

journal_title：Journal of clinical epidemiology

authors： Mueller KF,Meerpohl JJ,Briel M,Antes G,von Elm E,Lang B,Motschall E,Schwarzer G,Bassler D

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:To assess whether short message service (SMS) text messages sent as prenotification or postnotification reminders improve questionnaire response rates in randomized controlled trial (RCT) follow-up. STUDY DESIGN AND SETTING:Three "trials within a trial" assessed text message notifications sent before or aft...

journal_title：Journal of clinical epidemiology

authors： Keding A,Brabyn S,MacPherson H,Richmond SJ,Torgerson DJ

更新日期：2016-11-01 00:00:00